I mean, the obvious advantage and only advantage is to show off your gpu, Chris. If you have tempered glass that's a no-brainer. But the disadvantage is that your gpu will be close to the glass and reduce airflow, so you need to think about that before mounting it and either use a hybrid cooler or a custom loop, or have a lot of airflow moving through your case, which many tempered glass cases are kind of restrictive with to begin with. Whatever though, it looks cool I guess. I use a black metal box with a bunch of holes in it, if it's doing any glow-y RGBing I wouldn't know