We've got 2 machines running it right now. It cleaned the living hell out of my system, stripping the dye from previous fluid out of my PETG tubing and making it clear again. As others have said it's a show fluid so it's not the best for longevity but Primochill says as long as you don't run your pump at full speed, don't run your system more than 8 hours at a time, and change the fluid out after 6 months you will be all good.
Hopefully none of your components are aluminum - as that will really mess the fluid up.
Don't mix this with anything else, run it on its own and it will be just fine.
You probably won't have to do much flushing at all. The fluid is abrasive enough to clean it out but opaque enough to not show grime in the fluid.